Rilmenidine Phosphate

Research use only, not for human use.

Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.

Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.(In Vitro):Rilmenidine provides antihypertensive efficacy comparable with that of diuretics, beta-blockers, calcium channel blockers, and angiotensin-converting enzyme (ACE) inhibitors.Rilmenidine phosphate (25-100 μM; 24 hours) inhibits K562 cell proliferation.(In Vivo):Rilmenidine phosphate-treated N171-82Q mice (i.p.; 4-times a week) displays significant improved forelimb grip strength and all limbs grip strength from 12 to 22 weeks of age.Rilmenidine phosphate decreases levels of mutant huntingtin.

Rilmenidine provides antihypertensive efficacy comparable with that of diuretics, beta-blockers, calcium channel blockers, and angiotensin-converting enzyme (ACE) inhibitors.Rilmenidine phosphate (25-100 μM; 24 hours) inhibits K562 cell proliferation. Cell Proliferation Assay Cell Line:K562 cells Concentration:25, 50, 100 μM Incubation Time:24 hours Result:Dose-dependently inhibited K562 colony formation.

Rilmenidine phosphate-treated N171-82Q mice (i.p.; 4-times a week) displays significant improved forelimb grip strength and all limbs grip strength from 12 to 22 weeks of age.Rilmenidine phosphate decreases levels of mutant huntingtin.

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Others

Other Targets

I(1) imidazoline receptor

Others-Field

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85409-38-7

278.24

C10H19N2O5P

>98% (HPLC)

In Vitro:?H2O : 83.33 mg/mL (299.49 mM)

C1CC1C(C1CC1)NC1=NCCO1.OP(=O)(O)O

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(-20℃)

With Ice Pack

≥ 2 years